X-Men: Mutant Apocalypse is an action game developed and published by Capcom for the Super Nintendo Entertainment System in 1994. The game is based on the X-Men comic book franchise from Marvel Comics. It was the second game Capcom released based on the franchise, the other being a fighting game titled X-Men: Children of the Atom, also released in 1994.

In Mutant Apocalypse, players control five of the X-Men: Beast, Cyclops, Gambit, Psylocke, and Wolverine. After guiding each of them through their own dedicated levels, players can then select which level to complete next as well as the team member to complete it with. The end goal is to defeat Magneto on his Avalon space station. The game was well received by critics.

The player takes control of five X-Men who each have their own objectives, and different moves and capabilities activated by certain control combinations. The player has a limited number of lives that count for all five X-Men and not one individually.

The levels may be played in any order. At the end of each level, a boss must be battled and defeated. The next three levels are linear and require each boss level to be defeated. This is followed by two straightforward boss battles in the Danger Room. Finally only one of the X-Men can be selected, each one going through a different end level.

After beating the first five stages, a password can be acquired. The game has health pickups, as well as extra lives in the form of collecting three "X" icons hidden throughout each stage.