Super Bases Loaded is a baseball video game produced by Jaleco for the Super Nintendo Entertainment System in 1991. It is the fifth overall installment of the Bases Loaded series, and first installment of the secondary series for the Super NES. This game was originally released in Japan under the title Super Professional Baseball (スーパープロフェッショナルベースボール) in Japan.

The North American version includes a sponsorship from Ryne Sandberg, like Bases Loaded 3 for the NES.