Based on the famous comics series about good cowboy Lucky Luke.

In this game, Lucky Luke has to arrest the four Dalton brothers – Averell, William, Jack, and Joe. Gameplay involves progressing from level to level, shooting enemies (bad cowboys, jailbreakers, and hostile Indians) with Luke's revolver, collecting various items like bullets, dynamites or sheriff stars, running, jumping, ducking, and climbing. Locations vary from forts, towns and jails, to mines, a train, and a haunted saloon. On every level, Luke will have to complete different side objectives to progress, like freeing a bank director, collecting gold nuggets for a miner in exchange of some nitroglycerine, or building a totem for the Apache. Some levels end with a boss battle, usually against one of the Dalton brothers.

Different arcade sequences between levels involve chasing the Dalton brothers, riding Luke's faithful horse Jolly Jumper, running away from a tornado, or navigating a raft, among other things. Bonus level arcade sequences include a wrestling challenge with Jolly, bottle shooting, or a revolver barrel roulette.

The game uses a password system to start directly from certain points in the game. It was made in French, English, German and Spanish.