Teenage Mutant Ninja Turtles(TMNT): The Hyperstone Heist, released in Europe as Teenage Mutant Hero Turtles: The Hyperstone Heist and in Japan as Teenage Mutant Ninja Turtles: Return of the Shredder, is a 1992 side-scrolling beat 'em up game developed and published by Konami for the Sega Genesis, based on the Teenage Mutant Ninja Turtles comic book characters. It was Konami's debut title for the Genesis. The game was re-released as part of Teenage Mutant Ninja Turtles: The Cowabunga Collection in 2022.

April O'Neil is reporting from Liberty Island when, in a sudden flash of light, she and her audience witness Manhattan Island suddenly starting to shrink. Shredder then hijacks the airwaves and announces to the world that this was only a demonstration of the power of the Hyperstone, the treasure of Dimension X. With the Hyperstone in his possession, he now has the power to take over the world. The Turtles have no choice but to go after Shredder and stop him.

The gameplay of The Hyperstone Heist is heavily based on the second TMNT arcade game, Turtles in Time, which was ported to the Super NES during the same year. The controls are similar to Turtles in Time, but the ability to dash is now assigned to a specific button and the player can no longer throw enemies towards the screen.

The game shares nearly the same soundtrack and sound effects as Turtles in Time, but the music plays faster in The Hyperstone Heist. Though there are less than half as many levels as Turtles in Time, each level is longer. Furthermore, The Hyperstone Heist has a more aggressive enemy AI and faster-moving gameplay.

There are a total of five levels ("New York City", "A Mysterious Ghost Ship", "Shredder's Hideout", "The Gauntlet", and "The Final Shell Shock"), which comprise a combination of new levels created specifically for this game and ones based on levels from the first arcade game and Turtles in Time. The bosses include Leatherhead, Rocksteady, Tatsu, Baxter Stockman, Krang, and Super Shredder.