Bo Jackson Baseball is a baseball video game for the Nintendo Entertainment System, Commodore Amiga, TurboGrafx-16 and MS-DOS. It features athlete Bo Jackson, then a star in professional baseball and a former professional football player. In Europe, it was released by Mindscape as TV Sports: Baseball, part of the TV Sports series including TV Sports: Basketball and other games based on hockey and American football.

The player can select from five to nine innings. Players can choose to throw five different kinds of pitches either slowly, normal, or fast.

One or two players can select exhibition mode or playoff mode. CPU vs CPU or CPU vs CPU quick mode can speed a tournament, to see the stats of that particular match and quickly end tournaments. The game uses city names but not the team names because of lack of proper licensing with Major League Baseball.[1] The players are purely fictional and cannot be edited. Some of the player names are parodies, such as Baltimore's "Kenrip" resembling "Cal Ripken".