The Simpsons: Bart vs. the Juggernauts is an action video game released in 1992 for the Game Boy. It was developed by Imagineering and published by Acclaim. The plot stars Bart from The Simpsons in a game show based on American Gladiators, in which he has to compete in challenges to earn money. Critics gave The Simpsons: Bart vs. the Juggernauts average reviews.

In The Simpsons: Bart vs. the Juggernauts, the player controls cartoon character Bart Simpson from the animated television series The Simpsons. He is participating in a weekly game show called Juggernauts USA, based on the television program American Gladiators, in which he has to run through obstacle courses, battle huge muscle-bound "juggernauts", and do various other challenges. There are a total of seven challenges that change from week to week. To make it onto the next week's episode of Juggernauts USA and avoid being eliminated, Bart must collect a certain amount of money from the challenges.

Each of the four levels of The Simpsons: Bart vs. the Juggernauts are made up of an episode of the game show Juggernauts USA. Every challenge is based on a character from The Simpsons. For example, there is one challenge in which Bart has to run an obstacle course in Apu's Kwik-E-Mart store. Another one is Dr. Marvin Monroe's "Hop, Skip and Fry", in which Bart jumps on a floor of tiles that randomly shifts from being safe to electrifying. The others include basketball, skateboarding, a juggernaut fighting match, and a match of shoving at Moe's Tavern. The characters Kent Brockman and Marvin Monroe are the game show's commentators; after the completion of a challenge they comment on Bart's performance.