Ken Griffey Jr. Presents Major League Baseball is an SNES and Game Boy video game whose star athlete is, as the name implies, Ken Griffey Jr., a baseball player for the Seattle Mariners. While it does include real life teams and their stadiums, it doesn't include names of real players, rather the names are usually based on famous people with the exception of Ken Griffey Jr who is the only one that uses his real name.

The game was scaled down tremendously to work on the Game Boy though it worked similar to the rest of the series. Since it was released in 1997, it had the 1996 roster instead. The game occasionally had slowdown too and there was only one stadium to conserve space. The game had Super Game Boy features as well. It also had a license from not only Major League Baseball, but also the Major League Baseball Association. Meaning that real MLB players' names were legally used for the GB version. Unlike the SNES version where it was developed by Software Creations, Nintendo developed the Game Boy version.