Teenage Mutant Ninja Turtles 2: Battle Nexus is a third person beat 'em up video game, released in 2004 by Konami. It is the sequel to Teenage Mutant Ninja Turtles and is based on the 2003 TV series.

The game has cel-shaded graphics, four-player gameplay, and includes the first TMNT arcade game as an unlockable bonus. Teenage Mutant Ninja Turtles 2 Battle Nexus is based mostly on the end of the second season of the 2003 animated TMNT series. The game also has 4 tournaments consisting of waves of enemy attacks.

The cinematic cutscenes are adapted from various episodes in the cartoon series featuring the Feudal Japan arc in which the origin of Oroku Saki is discovered.