Super Mario Advance 4: Super Mario Bros. 3 is the Game Boy Advance remake of the 1988 NES game Super Mario Bros. 3, and is the fourth and final entry in the Super Mario Advance series of games on the GBA. It boasts similar graphics and sound to the Super Mario All-Stars version, and makes use of the e-Reader to support additional content. It features a remake of Mario Bros. identical to that found in the Super Mario Advance games that came before it. It also has rumble support if played on a Game Boy Player.

The first release of the game was bundled with a few e-Reader cards. Two groups of cards, referred to as series, were also sold as separate products. By scanning these special cards into the e-Reader, players are able to unlock items, videos and, most significantly, new levels in the game. One notable item is the Cape Feather from Super Mario World, which allows Mario to transform into Caped Mario. Included with the game were also two Switch cards that the player could activate and deactivate the effects of by scanning them: the Orange Switch and the Blue Green Switch. The e-Reader feature is still present in the European version, but is disabled and inaccessible, despite being fully translated. This is due to the e-Reader not releasing in Europe, despite being planned to. The e-reader's functionality can be forcibly accessed in the European version by corrupting a save file.

The game was re-released on the Wii U's Virtual Console service in Japan on December 29, 2015, and later in North America on January 21, 2016, in Europe on March 10, 2016, and in Australia on March 11, 2016. All releases on the Wii U automatically include all levels that were accessible via e-Reader cards, including levels that had previously only been released in Japan.