Mat Hoffman's Pro BMX is a BMX video game endorsed by Mat Hoffman and the first game to be published by Activision under the Activision O2 label. It is similar to the Tony Hawk's series and competed directly with Acclaim Entertainment's Dave Mirra Freestyle BMX.[1] Despite a planned release in fall of 2000, the game was released in May 2001 for the PlayStation and Game Boy Color, followed by Dreamcast, Microsoft Windows and Game Boy Advance.

Mat Hoffman's Pro BMX uses a tweaked version of the game engine used in a similar video game, Tony Hawk's Pro Skater. The goal of the game is to successfully perform and combine different tricks on a BMX bike, with successful executions adding to the player's score. The point value of the trick is based on time maintained, degrees rotated, number of tricks performed in sequence, and the number of times the tricks have been used (the more often a trick is used, the less it's worth). Successful tricks also add to the player's special meter, which, once full, allows for the execution of "signature moves" which are worth more than normal tricks. Grinds, lip tricks, and manuals (wheelies) are included in the game to help the player link tricks together into combos. Bails (falling off the bike due to poor landing) cause for no points to be awarded for the attempted trick or combo, and resets the special bar to empty.

The player can play as one of eight different professional BMX riders, including Mat Hoffman, Rick Thorne, Dennis McCoy and Mike Escamilla. Tony Hawk is featured as a hidden character, as is a fictional elderly character named "Granny". Each rider has their own individual stats, bikes, and trick-sets.

Ten levels exist in the game (including two remade levels from Pro Skater), consisting of street, vert, and dirt track-oriented courses. Secret areas, point-bonuses, and many breakable objects are scattered amongst the levels.