Dr. Mario & Puzzle League (also parsed Dr. Mario / Puzzle League,[1] known as Dr. Mario & Panel De Pon in Japan) is a "2 in 1" game for the Game Boy Advance. Dr. Mario is an enhanced remake of the original Dr. Mario, with many of the graphics similar that of Dr. Mario 64.

Puzzle League's name comes from Pokémon Puzzle League, a game based on Panel de Pon. This version, however, is a very simple form of the game.

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