Mickey's Space Adventure is a graphic adventure game for a number of platforms. It was designed by Roberta Williams and released by Sierra On-Line in 1984. It features the Disney characters Mickey Mouse and Pluto.

Written in 1984 by Roberta Williams, the game was a joint project with Disney prior to their collaboration on The Black Cauldron. The game was intended for children. While there were several similar games featuring Disney characters, Mickey's Space Adventure is not considered part of a larger series. The PC version was released on two 360 KB 5¼" disks.